Duration: hours oral ; 2 hours IV. This depends on how your body responds to the drug. Audiometry is recommended for patients receiving prolonged high-dose IV therapy. Potassium supplements or potassium-sparing diuretics may be used concurrently to prevent hypokalemia. Salicylates: May cause salicylate toxicity.
Are there any alternatives? This includes potassium levels. Antidiabetics: Decreases hypoglycemic effects. MonitoringParameters Correct hypovolaemia, hypotension, and severe electrolyte disturbances prior to treatment initiation. Take Lasix exactly as prescribed by your here. Alternatively, usual maintenance dose of mg daily may be given.
Alternatively, usual maintenance dose of mg daily may be given. Elderly: Initiate at lower doses. Oral Oliguria in acute or chronic renal failure Adult: In patients with chronic renal insufficiency: Initially, mg, may be increased in increments of mg every hours if satisfactory response is not achieved. Max: 1, mg 24 hourly. Oral Oedema Adult: Cases associated with CHF, liver cirrhosis, and renal disease, including nephrotic syndrome: Initially, 40 mg daily preferably in the morning, adjusted as necessary according to patient response.
Mild cases may respond to 20 mg daily or 40 mg on alternate days. In some cases, 80 mg or more daily in 1 or 2 divided doses may be required. Max: 40 mg daily.
Parenteral Oedema Adult: Initially, mg via slow IV or IM inj, may be increased in increments of 20 mg every 2 hours if necessary. Max: 1, mg daily. Child: 0. Max: 20 mg daily. Administration Oral Solution: May be taken with or without food. Reconstitution IV infusion: Dilute with 0. Incompatibility Incompatible with injections of amrinone, ciprofloxacin, diazepam, diltiazem hydrochloride, dobutamine hydrochloride, dopamine hydrochloride, droperidol, doxorubicin, gentamicin, isoprenaline, labetalol hydrochloride, lidocaine, metoclopramide, midazolam hydrochloride, milrinone lactate, morphine, pethidine, nicardipine hydrochloride, vecuronium bromide, parenteral nutrient solutions, cisatracurium besilate, levofloxacin, phenylephrine, vasopressin, vincristine.
May be precipitated with strongly acidic solutions such as infusions with ascorbic acid, epinephrine, norepinephrine, and tetracycline. Contraindications Hypersensitivity to furosemide and sulfonamides.
Anuria, renal failure with anuria not responding to furosemide; renal failure due to poisoning by nephrotoxic or hepatotoxic agents; renal failure associated with hepatic coma, electrolyte disturbances e.
Special Precautions Patient with prediabetes or diabetes mellitus; prostatic hyperplasia, urinary stricture, impaired micturition, gout, hepatorenal syndrome, hypoproteinaemia e. Not recommended in patients at high risk for radiocontrast nephropathy.
Renal and hepatic impairment. Children and elderly. Adverse Reactions Significant: Fluid and electrolyte depletion, symptomatic hypotension, asymptomatic hyperuricaemia, nephrotoxicity, ototoxicity e.
Blood and lymphatic system disorders: Haemoconcentration. This medication is available in an injectable form to be given directly into a vein IV or the muscle IM by a healthcare professional. The adverse side effects may be worsened with use of alcoholic beverages. If you miss a dose, take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and take your next dose at the regular time.
Do not take two doses of furosemide at the same time. Lasix Dosage Take furosemide exactly as prescribed by your doctor. Follow the directions on your prescription label carefully. The furosemide dose your doctor recommends will be based on the following: the condition being treated other medical conditions you have other medications you are taking how you respond to this medication your weight your age The recommended dose range of furosemide for the treatment of edema in adults is 20 to 80 mg as a single dose.
If administering twice daily, give last dose no later than 5 pm to minimize disruption of sleep cycle.
IV route is preferred over IM route for parenteral administration. Tablets may be crushed if patient has difficulty swallowing. Do not administer discolored solution or tablets. Infusion stable for 24 hr at room temperature. Do not refrigerate. Protect from light. Use an infusion pump to ensure accurate dose. Y-Site Compatibility.
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Speak to your doctor about how drug off should be managed. The Potential Side Effects Of Here There are ample ingredients available in this product which make this medicine unique to remover liver, cardiac, and nasal issues. VETgirl cannot guarantee your satisfactory completion of any CE course or that you will be granted CE credit for having completed a course.
Please note that you are using these links at your own risk. Lasix's effect is take strong. You agree that all safely arising under Internet related to your use or access of the Sites, the products and services offered therein, and these Terms and Conditions shall be brought solely in the federal and state lasix situated in the County of Ramsey, State of Minnesota.
Moreover, this medicine stays effective within 90 days from opening dog seal. These Terms and Conditions constitute a legally binding agreement how you and VETgirl regarding your use and access to the Sites.
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Your electrolyte levels will need regular monitoring and your blood may need occasional testing for diabetes. VETgirl Content is the property of VETgirl, its licensors, sponsors, partners, advertisers, content providers or other third parties and is protected by law. Otherwise, it push affect the rest lasix the parts of the body.
As a result, your pet becomes weak and can even die. Dietary Instructions Furosemide is divided into two categories where the loop diuretic is used to treat the fluid retention. It balances the sodium level in kidneys. On the other hand, it works as the recovery from heart failure. However, make sure that your dog has taken plenty of water simultaneously while it is taking this drug.
You need to pay attention to the water balance of your pet. Otherwise, it will not work on their body. Again, the dogs should take the potassium-rich foods such as the bananas, orange-juice which keep dehydrates to your pet.
Then, it will be more useful to recover cardiac failure, kidney problem, etc. Moreover, it will keep your puppy healthier. The Potential Side Effects Of Furosemide There are ample ingredients available in this product which make this medicine unique to remover liver, cardiac, and nasal issues. So, the chances of a cardiac problem, jaundice like severe diseases become low.
Blood-Pressure Controller: Moreover, this medicine is beneficial for controlling the high blood pressure. May interact with a number of other drugs including potassium, lithium, corticosteroids, digoxin, phenytoin, and methotrexate as well as those that also lower blood pressure. Note: In general, seniors or children, people with certain medical conditions such as liver or kidney problems, heart disease, diabetes, seizures or people who take other medications are more at risk of developing a wider range of side effects.
View complete list of side effects 4. Bottom Line Lasix is a strong diuretic that increases urination which relieves excess fluid from the body. This may also lead to the depletion of certain electrolytes, such as potassium.
Tips Dosages vary from individual to individual and people taking high dosages may need extra monitoring by their doctor. Some individuals may only need to take Lasix two to four times per week. You may be more sensitive to sunlight while taking Lasix. Tell your doctor if you develop diarrhea or vomiting while taking Lasix. Get up slowly when going from a lying down or sitting position to standing because Lasix may make you feel dizzy.
Your electrolyte levels will need regular monitoring and your blood may need occasional testing for diabetes. If you already have diabetes, be aware that Lasix may increase your blood glucose levels. No Unlawful, Prohibited, or Reckless Use. As a condition of your use of the Sites and the services and products therein, you warrant to VETgirl that you will not use the Sites for any purpose that is unlawful or prohibited by these Terms and Conditions. You may not use the Sites in any manner that could jeopardize your safety or the safety of others, including texting, streaming, e-mailing, or using the Sites while driving, running, or participating in other activities that require your attention to safety.
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years: mg/kg PO q24hr or q12hr; individual dose not to exceed 6 mg/kg/dose Excessive diuresis may cause dehydration and electrolyte loss in elderly; lower initial dosages and more.
Increased liver enzymes 6. In isolated cases, intravenous administration of furosemide within 24 hours of taking chloral hydrate may lead to flushing, sweating attacks, restlessness, nausea, increase in blood pressure, and tachycardia.
Broad-spectrum antibiotic and beta-lactamase source effective against selected gram-positive, gram-negative, and anaerobic organisms. Serum and urine electrolyte determinations are particularly important when the patient is vomiting profusely or receiving parenteral fluids.
Furosemide is extensively bound to plasma proteins, mainly to albumin. Coli, Klebsiella, Proteus, and Pseudomonas. Do not mix in same solution.
The peak effect occurs within the first half hour. Nursing Mothers: Because it appears in breast milk, caution should be exercised when furosemide is administered to a nursing mother. Interactions: May be inactivated in solution with aminoglycosides, gentamicin.
Literature reports indicate that coadministration of indomethacin may reduce the natriuretic and antihypertensive effects of furosemide in some patients by inhibiting prostaglandin synthesis. I would listen and question the order. Has 20 years experience.
Peak plasma concentrations increase with increasing dose but continue reading do not differ among doses.
The possibility exists of exacerbation or activation of systemic lupus erythematosus.
The addition of sulbactam improves ampicillin's keep reading activity against beta-lactamase-producing strains resistant to penicillins and cephalosporins.
Tell your doctor if you develop diarrhea or vomiting while taking Lasix. Lasix's effect is very strong. Has 41 years experience. Potentiation occurs with ganglionic or peripheral adrenergic blocking drugs. Accordingly, serum levels of these electrolytes should be determined periodically.
What are the so-morbidities? Usual dose: 1.
Nursing Implications: Each single dose, properly diluted, over 30 to info minutes, up to 2 hours in peds patients. Push may add to or potentiate the therapeutic effect of other antihypertensive drugs. The risk is greater with higher dosages, injectable Lasix, severe renal impairment, low protein phlebitis, and concomitant therapy with other drugs that are also toxic to the ears.
In general, mins selection for the elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal or cardiac function, and of concomitant disease or other drug therapy. Although furosemide is more rapidly absorbed from the oral solution 50 minutes than from the tablet 87 minutespeak plasma levels and area under the plasma concentration-time curves do not differ significantly.
In hepatic coma and in states of electrolyte depletion, therapy should not be instituted until the basic condition is improved. Avoid should be corrected or the drug temporarily withdrawn.
Feb lasix, You can go slower
So really, if you were pushing 10mL, you should have pushed it for at least 10 min. Because elderly patients are more likely to have decreased renal function, care come here be taken in dose selection and it may be useful to monitor renal function. Have the gotten this before?
May increase blood glucose levels and affect laboratory test results. She does live in a ALF but they will not monitor but just check on her.
Has 41 years experience. Furosemide Injection is indicated as adjunctive therapy in acute pulmonary edema. Are they SOB and in failure?
Concomitant use of cyclosporine and furosemide is associated with increased risk of gouty arthritis secondary to furosemide-induced hyperuricemia and cyclosporine impairment of renal urate excretion. Furosemide has been shown to cause unexplained maternal deaths and abortions in rabbits at 2, 4, and 8 times the maximal recommended human oral dose.
This drug is known to be substantially excreted by the kidney, and the risk of toxic reactions to this drug may be greater in patients with impaired renal function.
Interactions: Aminoglycosides, others. Do not mix with other drugs in a syringe or infusion bottle. Nursing Implications: A single dose over 30 minutes as an intermittent infusion. Discontinue primary IV infusion during administration. Slow infusion rate for pain along venipuncture site. The addition of sulbactam improves ampicillin's bactericidal activity against beta-lactamase-producing strains resistant to penicillins and cephalosporins.
Broad-spectrum antibiotic and beta-lactamase inhibitor effective against selected gram-positive, gram-negative, and anaerobic organisms. Indications: Treatment of skin and skin structure and intraabdominal and gynecologic infections due to susceptible strains of specific organisms. Usual dose: 1. If your little voice inside your head is questioning the safety I would listen and question the order. Has 12 years experience. If you can't monitor, I wouldn't given it. Sounds like she should be getting it in the ER if she's in a ALF, those aren't designed for acute care situations, and I don't even think a nursing home would give that.
I would refuse giving any meds that I do not feel comfortable giving. You should tell your Supervisor. Has 30 years experience.
Feb 15, I run a silled facility. We have a policy to give IV Lasix, but if someone is that unstable, I'm far more comfortable sending them out to the hospital. The skin of some patients may be more sensitive to the effects of sunlight while taking furosemide.
Hypertensive patients should avoid medications that may increase blood pressure, including over-the-counter products for appetite suppression and cold symptoms. Laboratory Tests: Serum electrolytes, particularly potassium , CO2, creatinine and BUN should be determined frequently during the first few months of furosemide therapy and periodically thereafter.
Serum and urine electrolyte determinations are particularly important when the patient is vomiting profusely or receiving parenteral fluids. Abnormalities should be corrected or the drug temporarily withdrawn.
Other medications may also influence serum electrolytes. Reversible elevations of BUN may occur and are associated with dehydration, which should be avoided, particularly in patients with renal insufficiency. Urine and blood glucose should be checked periodically in diabetics receiving furosemide, even in those suspected of latent diabetes. Furosemide may lower serum levels of calcium rarely cases of tetany have been reported and magnesium. Accordingly, serum levels of these electrolytes should be determined periodically.
Drug Interactions: Furosemide may increase the ototoxic potential of aminoglycoside antibiotics, especially in the presence of impaired renal function. Except in life-threatening situations, avoid this combination. Furosemide should not be used concomitantly with ethacrynic acid because of the possibility of ototoxicity. Patients receiving high doses of salicylates concomitantly with furosemide, as in rheumatic diseases, may experience salicylate toxicity at lower doses because of competitive renal excretory sites.
There is a risk of ototoxic effects if cisplatin and furosemide are given concomitantly. In addition, nephrotoxicity of nephrotoxic drugs such as cisplatin may be enhanced if furosemide is not given in lower doses and with positive fluid balance when used to achieve forced diuresis during cisplatin treatment.
Furosemide has a tendency to antagonize the skeletal muscle relaxing effect of tubocurarine and may potentiate the action of succinylcholine. Furosemide combined with angiotensin converting enzyme inhibitors or angiotensin II receptor blockers may lead to severe hypotension and deterioration in renal function, including renal failure.
An interruption or reduction in the dosage of furosemide, angiotensin converting enzyme inhibitors, or angiotensin receptor blockers may be necessary. Furosemide may add to or potentiate the therapeutic effect of other antihypertensive drugs. Potentiation occurs with ganglionic or peripheral adrenergic blocking drugs.
Furosemide may decrease arterial responsiveness to norepinephrine. However, norepinephrine may still be used effectively.
In isolated cases, intravenous administration of furosemide within 24 hours of taking chloral hydrate may lead to flushing, sweating attacks, restlessness, nausea, increase in blood pressure, and tachycardia. Use of furosemide concomitantly with chloral hydrate is therefore not recommended. Phenytoin interferes directly with renal action of furosemide. Methotrexate and other drugs that, like furosemide, undergo significant renal tubular secretion may reduce the effect of furosemide.
Conversely, furosemide may decrease renal elimination of other drugs that undergo tubular secretion. High-dose treatment of both furosemide and these other drugs may result in elevated serum levels of these drugs and may potentiate their toxicity as well as the toxicity of furosemide. Furosemide can increase the risk of cephalosporin-induced nephrotoxicity even in the setting of minor or transient renal impairment. Concomitant use of cyclosporine and furosemide is associated with increased risk of gouty arthritis secondary to furosemide-induced hyperuricemia and cyclosporine impairment of renal urate excretion.
One study in six subjects demonstrated that the combination of furosemide and acetylsalicylic acid temporarily reduced creatinine clearance in patients with chronic renal insufficiency. There are case reports of patients who developed increased BUN, serum creatinine and serum potassium levels, and weight gain when furosemide was used in conjunction with NSAIDs.
Literature reports indicate that coadministration of indomethacin may reduce the natriuretic and antihypertensive effects of furosemide in some patients by inhibiting prostaglandin synthesis. Indomethacin may also affect plasma renin levels, aldosterone excretion, and renin profile evaluation. Carcinogenesis, Mutagenesis, Impairment of Fertility: Furosemide was tested for carcinogenicity by oral administration in one strain of mice and one strain of rats.
A small but significantly increased incidence of mammary gland carcinomas occurred in female mice at a dose Furosemide was devoid of mutagenic activity in various strains of Salmonella typhimurium when tested in the presence or absence of an in vitro metabolic activation system, and questionably positive for gene mutation in mouse lymphoma cells in the presence of rat liver S9 at the highest dose tested.
Furosemide did not induce sister chromatid exchange in human cells in vitro, but other studies on chromosomal aberrations in human cells in vitro gave conflicting results. In Chinese hamster cells it induced chromosomal damage but was questionably positive for sister chromatid exchange.