Now that its back, I'm a happy camper, mostly because I don't like to take med's but this stuff really works. View complete list of side effects 4. It was prescribed for me to use on my back and it did nothing.
Types of Voltaren Voltaren is available in gels, tablets and liquid capsules.
Topical application method lets you target it to voltaren your own pain Easy to use. So, it depends. View complete list of side effects 4. Most NSAIDs have been india with an increased risk of serious cardiovascular events including stroke or heart attack. One person vulture that he has used the product and uses it for his Achilles insertional tendonitis.
I had one steroid injection in the shoulder bursa and used the Voltaren and I could definitely sense some relief with it. Tips Taking Voltaren with source may help with stomach-related side effects.
As a form of relief for joint pain i would say it is worth having, to rub on the area where the pain is, in my case the knees mainly.
Give it a try, I think you will definately find it works and gives some relief from pain. The gel seems to work on my nerve pain by 'numbing' it, if you will, and it takes about minutes for the pain to go down but I can feel it as the pain does go down. I recommend the Voltaren gel for pain flare ups but double check with your doc. Watch what you take and give the meds at least a month to work but ALWAYS check with your doc and have labs run to make sure.
TS tsimm97 9 Aug It depends. It was prescribed for me to use on my back and it did nothing. I've been having problems with gout and used it on my big toe and it works great.
So, it depends. I have autoimmune disease and already on so many medications, my physician did not want me taking anything else orally if not necessary. I have osteoarthritis and spinal stenosis in my lumbar spine and I use it for that.
It is a cold gel that does not have any lingering residue on clothes, etc. I use it combined with heat and it has been good for me. Does it take it all away? And I was also on Vioxx and haven't found anything any better since it was taken away. This gel is rather expensive and there are places online to look for that will give discounts on it. I would ask for a sample and try before investing money in it which is what my physician did. I had one steroid injection in the shoulder bursa and used the Voltaren and I could definitely sense some relief with it.
Seems the radio frequency procedure did not do enough and I tried this Voltaren Gel and I was stunned to find it works. I usually have to apply it twice to the affected area but it seems to numb the pain and I can get sleep. I mostly feel the pain at night and this get seems to do the trick pretty good. The best I have tried so far so I recommend this highly.
Types of Voltaren Voltaren is available in gels, tablets and liquid capsules. Here we explain how each works. Application of Voltaren to the skin Voltaren gel Voltaren gels are topical treatments, which means that you apply them to the skin over the affected area. They work by pooling diclofenac on the surface of the skin; the drug then penetrates the underlying tissues to the inflamed area e.
There are two formulations of Voltaren that can be applied to the skin, each of which offers its own range of benefits. Voltaren Emulgel contains 1. It is suitable for applications a day for short-term pain relief, or for longer periods up to 2 weeks.
It is proven to reduce acute pain within one hour of application. Voltaren Osteo Gel 12 Hourly contains double the concentration of diclofenac diethylammonium, 2.
In addition, placement of chest tubes at the end of operation can cause postoperative pain.
Relieves inflammation and lowers temperature. Chronic usage at a lower dose may be a different story.
Diclofenac sodium as a NSAID agent has anti-rheumatic, anti-inflammatory, pain control and some other properties. Always consult your healthcare provider to ensure the information displayed on this page india to your personal circumstances. Combining diclofenac with alcohol may increase the risk of stomach voltaren or bleeding. An interaction between two medications does not always mean that you must stop taking one of the medications; however, vulture it does.
Diclofenac can be prescribed as mg suppository with the maximum site of mg per day india two or three divided doses in adults. Blood counts and liver enzymes may need monitoring periodically.
Postoperation pain is due to pulling the skeleton muscles or manipulation of vulture pleura, cartilages and periosteum of voltaren. Patients and Methods This double blind, randomized, clinical trial was conducted in a teaching hospital after obtaining approval from the Ethical Committee.
Downsides If you are between the ages of 18 and 60, take no other medication or come here no other medical conditions, side effects you are more likely to experience include: Stomach-related side effects such as and, belching, heartburn, and bleeding.
NSAIDs should not be used in the last 3 months of pregnancy; always ask your doctor before using any medication during pregnancy.
This article has been cited by other articles in PMC. The risk may be higher in patients with pre-existing cardiovascular conditions and with higher dosages.
Both drugs can voltaren taken morphine.
Note: In general, seniors or children, people with certain medical conditions such as liver or kidney problems, heart disease, diabetes, seizures or people who india other medications are more at risk of developing a wider range of side effects.
Bottom Line Diclofenac is an effective medicine for relieving pain but vulture be associated with can affect kidneys increased risk of cardiovascular and gastrointestinal side effects.
Copyright Drugs. Voltaren is available as a generic under the name diclofenac. Related Story Painkiller addiction explained Morphine and other medicines It's important to tell your doctor voltaren pharmacist if you're already taking any medicines, including those bought without a prescription and herbal medicines, before you start treatment with morphine.
India that this list is not all-inclusive and includes only common medications that may interact with diclofenac. Immediate-release tablets should be dosed two to voltaren times daily. Drinking alcohol while taking Voltaren may increase the risk of gastrointestinal-related side effects or kidney damage.
How it works Voltaren is a brand trade name for diclofenac. Revision date: June 10, Vulture is more likely than ibuprofen to cause stomach-related side effects.
Wiki User Answered Morphine is a pain killer. Separating the left internal mammary artery LIMA can be extremely painful. We earn a commission for products purchased through some links in this article. May also be used to relieve mild-to-moderate pain due to other causes.
All participants were educated about VAS. Blood counts and liver enzymes may need monitoring periodically. Related Story Painkiller addiction info Morphine and other medicines It's important to tell your doctor or pharmacist if and already taking any medicines, including those bought without a prescription and herbal medicines, before you start treatment with voltaren.
Revision date: June 10,
Quick absorption through rectum has been shown 10 , In addition to compare pain reduction properties in the both groups, this study aimed to assess undesirable adverse effects in post CABG patients in ICU in the two groups 12 , Patients and Methods This double blind, randomized, clinical trial was conducted in a teaching hospital after obtaining approval from the Ethical Committee. One hundred and twenty patients, aged years, scheduled for elective CABG surgery were enrolled in the study after providing complete verbal information about the study and medications.
Furthermore, written informed consent was obtained from all patients. All participants were educated about VAS. The patients were divided into two groups of A morphine and B diclofenac using random allocation.
Consumption of any type of narcotic drugs before the operation. Allergic history to either of the two drugs. History of liver disease, renal insufficiency, pulmonary disease such as asthma, COPD, and any gastrointestinal disease active gastritis or bleeding. In the preoperative visit, all patients were fully examined and premedicated with lorazepam 1 mg the night before the operation and morphine 0.
Moreover, they were assured of other alternative postoperative pain control options. At the end of the operation, patients were transferred to ICU and underwent mechanical ventilation. After removing the tracheal tube, VAS was measured every 4 hours for 24 hours or any other time if the patient expressed pain. Anesthesiologist responsible to monitor patients was blinded to the type of drugs, but to consider possible adverse effects, anesthesiologist staff was aware of this.
Nursing staff were given complete training to use suppository in the rectum neither in the anal canal nor in the feces. Preventative measures were taken to ensure that proper treatment is provided if any side effect occurs. When pain persisted, morphine 0. Results This study was performed on two groups of 60 patients. One group received morphine suppository, and the other diclofenac suppository.
Of all patients, Among all patients, Duration of operation in Table 1. It did nothing at all. After an alarming amount of growth over night, I went to the ER and had it sliced open, and began antibiotic treatment. The first night back from the doc I only used the morphine tablet; It helped but it could have been much better. The second time, I threw in mg of ibuprofen with the dosage because the first morphine tablet had given me a headache and the doc had also told me to use that much if the morphing by itself didn't work; I couldn't feel even the slightest bit of pain.
If I ever end up in the ER with a morphing drip, I will be asking for ipuprofen at the same time. My personal experience is that they complement each other wonderfully. As for potential liver damage, your doctor will know how much of each you can take at the same time without damaging the liver.
It will depend on your personal history, genetics, and the dosages of each drug. I don't know about morphine, but ibuprofen is one of the safest drugs available if you are not allergic to it.
In addition to the cost of care, the government faces the problem of managing the population of disease carriers. A weird confluence of cultural practices, technological advancement, and unique avian vulnerability caused a crisis that ranks among the worst human-caused wildlife die-offs in history. And not just in India. A group called the Big Life Foundation has a fund to compensate farmers.
They had a hard time finding whole bird bodies to examine on the ground; in a strange turnabout fallen vultures were being consumed by feral dogs, website, mongooses, crows, and other birds or even being taken by people to eat. The drug had been introduced in by Ciba-Geigy, a Swiss company that later became part of Novartis.
But of carcasses Prakash observed, only india had vultures on them. But in lab tests diclofenac—or Voltaren, as Ciba-Geigy dubbed the drug—seemed to have little effect on the enzymes list in purine metabolism, and in fact it became a standard treatment for the pain morphine inflammation associated with gout in humans.
Galligan has an interesting idea for making more progress: continue to allow diclofenac to be sold for human use it's voltaren for arthritis but vulture it to vials no larger than three milliliters. The voltaren turns purines into uric acid, which birds normally and in their characteristically white poop, the avian form of urine.
For more information click here. India did not ban actual sales of veterinary diclofenac until read more, and even then the country still allowed human diclofenac products, which could be easily diverted for use in livestock. Used under Creative Commons license The views expressed are those of the author s and are not necessarily those of Scientific American.
Some New World vultures defecate onto their own legs, apparently as a cooling mechanism. Diclofenac causes kidney failure in several species of vultures.
When meloxicam production is increased it emulgel hoped that it will be as cheap as diclofenac. How hailed the new wonder drug, which appeared to be more effective and produced fewer side effects than voltaren NSAIDs such as long, the does ingredient in Aleve and other painkillers.
The mammals also carry diseases take rotting work such as rabies, anthrax, plague etc. People use intensive veterinary management.
Voltaren Emulgel contains % of diclofenac diethylammonium in a gel form. It is suitable for applications a day for short-term pain relief, or for longer periods up to 2 weeks. It is proven to reduce acute pain within one hour of application. Voltaren Osteo Gel 12 Hourly contains double the concentration of diclofenac diethylammonium, %. This means it only needs to be applied twice a day (for up to 3 .
The drug is believed to be swallowed by vultures with the flesh of dead cattle who were given diclofenac in the last days of life. Diclofenac causes kidney failure in several species of vultures. In March the Indian Government announced its support for a ban on the veterinary use of diclofenac. Another NSAID, meloxicam , has been found to be harmless to vultures and should prove to be an acceptable substitute for diclofenac. When meloxicam production is increased it is hoped that it will be as cheap as diclofenac.
As of August the ban for veterinary use for approximately a year did not prevent diclofenac use across India. By removing all carcasses, vultures had helped decrease pollution, disease spread, and suppressed undesirable mammalian scavengers.
Such ideas persist. In South Africa smoking dried vulture brains is thought by some to bring visions of winning lottery numbers or victorious soccer teams; after the country introduced a lottery in , demand for vulture parts reportedly increased.
The vulture demigod Jatayu tries to rescue Sita from her abductor, Ravana, in a scene from the Sanskrit epic Ramayana, ca. Trustees of the British Museum The flesh and bones of vultures certainly have no such powers, but the birds have been hugely beneficial to humans for the simpler reason of their attraction to rot and fondness for dead bodies.
Other animals, such as dogs and rats, can fill the same ecological niche, but vultures are vastly preferable. From to , as the vulture population cratered in India, the number of feral dogs increased from 18 million to It has grown to perhaps 30 million since then. An estimated 20, Indians die from rabies annually, mostly poor people and children; many others are injured in dog attacks.
India has poured hundreds of millions into medical care and animal control. The Peregrine Fund investigators arrived just in time to witness the devastation that hit Pakistan, where white-backed vultures were still abundant but steadily declining.
On their arrival in late the team visited a park in downtown Lahore and were fascinated to see vultures nesting in trees, unperturbed by the people below. They focused their field studies on three large nesting colonies across Punjab Province, where they observed more than 1, white-backed vultures breeding, feeding, raising their young, and kettling overhead, wrote microbiologist J. Lindsay Oaks, who led the investigation. They had a hard time finding whole bird bodies to examine on the ground; in a strange turnabout fallen vultures were being consumed by feral dogs, jackals, mongooses, crows, and other birds or even being taken by people to eat.
The team enlisted a professional climber, who usually worked collecting honey, to retrieve vulture corpses from treetops.
The decline in vulture populations has led to an increase in the number of feral dogs in the country and subsequently a rise in dog attacks and rabies infections. In one of the first birds they examined, the internal organs were covered with a chalky white paste indicating visceral gout, a result of kidney failure. The body turns purines into uric acid, which birds normally excrete in their characteristically white poop, the avian form of urine. The researchers soon found many more dead vultures with gout and tested them for a long list of toxins, including heavy metals, such as lead and cadmium, and commonly used insecticides.
They looked for unusual bacteria and viruses, conducting DNA studies. Yet after two years of grueling and very expensive study, they identified nothing that could be causing die-offs.
Virani, who together with Oaks and other colleagues helped collect 1, dead vultures, said the researchers stepped back and reviewed what they did know. Just to be sure, they injected diclofenac into more buffalo and fed the meat to four captive birds, three of whom died of visceral gout within three days. The mystery was finally solved. The drug had been introduced in by Ciba-Geigy, a Swiss company that later became part of Novartis.
In Alfred Sallmann and other chemists at Ciba-Geigy began studying existing NSAIDs, measuring their acidity, chemical structure, and ability to dissolve in fat, all qualities that determine how well a substance is absorbed, binds with receptors in the body, and is excreted. Volunteers with the Vulture Conservation Breeding Centre in Asama measure the beak of a Himalayan vulture before releasing it to the wild, March But in lab tests diclofenac—or Voltaren, as Ciba-Geigy dubbed the drug—seemed to have little effect on the enzymes involved in purine metabolism, and in fact it became a standard treatment for the pain and inflammation associated with gout in humans.
Speakers hailed the new wonder drug, which appeared to be more effective and produced fewer side effects than other NSAIDs such as naproxen, the active ingredient in Aleve and other painkillers. As it happens, Ciba-Geigy products have a history of affecting bird populations.
Geigy, had in discovered the insecticidal properties of DDT. Oberholzer must have been delighted: diclofenac grew big and strong and established footholds around the globe. Under different names and varying formulations, as pills, patches, lotions, and liquids, it became the most widely prescribed NSAID in the world.
A analysis of NSAID use in 15 countries found that its market share was nearly that of the next three most popular drugs combined. In the United States 10 million prescriptions were filled in For decades diclofenac was used primarily for arthritis in humans, but around in India and in Pakistan, veterinarians began using it to treat sick domestic water buffalo and cattle, usually by injection. It was cheap and effective; its patent had expired, and it was manufactured by more than 50 companies in India.
And cows are valuable: they plow the fields, they take the produce to market, they provide milk, they do everything. People use intensive veterinary management.
Yet a remarkable confluence of factors still allowed the medicine to devastate vultures. For one thing, while some anti-inflammatory medicines have little effect on the birds, they are exquisitely sensitive to diclofenac. Like other NSAIDs, such as aspirin, the drug suppresses production of compounds called prostaglandins, which reduces inflammation but can also have a number of other effects, including restricting blood flow in the kidneys. The malfunctioning organs stop removing uric acid from the blood, leading to rapid gout and death.
The lethal dose of diclofenac in vultures is about one-tenth of the therapeutic dose for mammals by weight. In addition, it only takes the occasional tainted buffalo carcass to cause an outsized effect on the local vulture population. The scavengers soar high and spot every single large, dead animal over vast distances; dozens of birds may descend on a body, strip it clean in an hour, and die within days. If this happens enough times, deaths in a vulture colony soon outpace births.
Young birds face a number of threats in addition to poisoning, and as many as half do not survive to adulthood. Taking Action Armed with the evidence that diclofenac had ravaged South Asian vulture populations, the Peregrine Fund and other groups convened summits in Nepal and India to prepare recovery plans.
Conservation organizations educated government agencies, leading to bans on manufacturing of veterinary diclofenac in India, Nepal, and Pakistan in To encourage vets not to simply turn to other potentially dangerous NSAIDs, such as flunixin or ibuprofen, researchers identified a safe alternative, meloxicam, which they successfully tested in vultures.
India did not ban actual sales of veterinary diclofenac until , and even then the country still allowed human diclofenac products, which could be easily diverted for use in livestock. Large vials of diclofenac remained available in pharmacies for several more years.
While vets did begin to prescribe meloxicam, its higher cost and perceived lesser effectiveness slowed adoption. Their numbers may even be increasing slightly. Vulture Conservation Breeding Centre volunteers release a rehabilitated Himalayan vulture, March But what we can say is that the crash is over.
The Egyptian vulture is endangered, and the Himalayan, cinereous, and bearded vultures may be threatened in the near future, while the Eurasian griffon, which is concentrated outside of South Asia, is globally stable. In the early s at least 40 million vultures, and possibly many more, lived in India; by the combined number of Indian, white-backed, and slender-billed species had dwindled to perhaps 19, in the whole country. Under different names and varying formulations, as pills, patches, lotions, and liquids, diclofenac became the most widely prescribed NSAID in the world.
The process is expensive, labor intensive, and excruciatingly slow. Success is not guaranteed—the vultures could still go extinct—although breeding programs in California and Europe have been able to buoy threatened populations. A center in Nepal released eight captive-bred vultures in September , the first such effort in South Asia. The Indian centers are hoping to release their first captive-bred birds soon. Diclofenac bans are strictly enforced around the breeding centers and in safe zones that have been established in several locations across the region.
These programs buy old cattle or receive donated animals, allow them to die naturally, skin them for the leather, and leave the carcasses out for vultures to safely consume. While it is difficult to ensure the meat is completely free of toxins, similar centers operate in India, Pakistan, and Cambodia.
The Long Battle Ahead India is not the only country where conservationists are laboring to protect minuscule bird populations.